{"product_id":"abbkine-prp1928-1mg","title":"Human Galectin-8 Protein, His tag (Animal-Free)","description":"\u003cp\u003e\u003cstrong\u003ePrimary Product Type:\u003c\/strong\u003e Cytokines and proteins\u003c\/p\u003e\u003cp\u003eGalectin-8 (Gal-8) is a lectin family member and is one of the tandem repeat-type galectins containing two carbohydrate recognition domains (CRD) connected by a linker region in a single peptide chain. The CRD is responsible for β-galactoside binding, and the binding partners for galectin-8 have been identified, including CD44 and a subset of integrins. Galectin-8 and integrins form complexes, subsequently leading to phosphorylation of paxillin and focal adhesion kinase (FAK), which activates signal pathways including MAPK-ERK and PI3K-AKT pathways. Galectin-8 is constitutively presented in the Liver, kidney, cardiac muscle, lung, and brain. Galectin-8 serves as an immunosuppressive protective role against autoimmune CNS inflammation, regulating the balance of Th17 and Th1 polarization.\u003c\/p\u003e","brand":"Abbkine","offers":[{"title":"1 mg","offer_id":48528885285088,"sku":"PRP1928-1mg","price":0.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/abbkine-logo-1_c761528d-99e4-4a40-ba37-7a1e094e2e87.png?v=1768031423","url":"https:\/\/rndmate.com\/products\/abbkine-prp1928-1mg","provider":"알앤디메이트","version":"1.0","type":"link"}