{"product_id":"anti-kpna2-antibody-fnab04635","title":"anti- KPNA2 antibody","description":"\u003cp\u003eanti- KPNA2 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eProduct Name\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eKPNA2 antibody\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e100µg\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eliquid\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eImmunogen affinity purified\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e≥95% as determined by SDS-PAGE\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eRabbit\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003epolyclonal\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIgG\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBACKGROUND\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFunctions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin\/substrate complex to the nuclear pore complex(NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and-beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMMUNOGEN INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ekaryopherin alpha 2(RAG cohort 1, importin alpha 1)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eRCH1, SRP1\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e55-58 kDa\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAPPLICATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eELISA, WB, IHC\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eRecommended Dilution\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWB: 1:500-1:2000; IHC: 1:20-1:200\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUNIPROT INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P52292\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eP52292\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMAGES\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab04635.jpg\" style=\"font-size: 0.875rem;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eImmunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab04635(KPNA2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab04635.jpg\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eHepG2 cells were subjected to SDS PAGE followed by western blot with FNab04635(KPNA2 antibody) at dilution of 1:1000\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-weight: 400;\"\u003eRELATED PRODUCTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003ca href=\"https:\/\/www.fn-test.com\/product\/p5346\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eRecombinant Human KPNA2\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003ca href=\"https:\/\/www.fn-test.com\/product\/eh1294\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eHuman KPNA2(Importin subunit alpha-2) ELISA Kit\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cspan style=\"font-weight: 400;\"\u003eSTATEMENT\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eManuals on the web are for your reference only, specifications are subject to the delivery manuals.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-weight: 400;\"\u003eFEATURED PRODUCT\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cbr\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":42430253793504,"sku":"FNab04635","price":290.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/fine_test_logo_380dd1ef-8205-4548-a04c-b89d1f448b07.jpg?v=1645519638","url":"https:\/\/rndmate.com\/products\/anti-kpna2-antibody-fnab04635","provider":"알앤디메이트","version":"1.0","type":"link"}