{"product_id":"anti-mms19-antibody-fnab05249","title":"anti- MMS19 antibody","description":"\u003cp\u003eanti- MMS19 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eProduct Name\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMMS19 antibody\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e100µg\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eliquid\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eProtein A+G purification\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e≥95% as determined by SDS-PAGE\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMouse\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003emonoclonal\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIgG2a\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBACKGROUND\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eKey component of the cytosolic iron-sulfur protein assembly(CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2\/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair(NER) and RNA polymerase II(POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2\/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor(ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMMUNOGEN INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMMS19 nucleotide excision repair homolog\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMMS19L\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e103 kDa\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAPPLICATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eELISA, WB, IF, IHC\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eRecommended Dilution\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWB: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:20-1:200\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUNIPROT INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q96T76\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eQ96T76\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMAGES\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab05249.jpg\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eImmunohistochemistry of paraffin-embedded human cervical cancer using FNab05249(MMS19 antibody) at dilution of 1:50\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab05249.jpg\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eHeLa cells were subjected to SDS PAGE followed by western blot with FNab05249( MMS19 Antibody) at dilution of 1:2000\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-weight: 400;\"\u003eRELATED PRODUCTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003ca href=\"https:\/\/www.fn-test.com\/product\/p2710\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eRecombinant Human MMS19\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003ca href=\"https:\/\/www.fn-test.com\/product\/fnab05248\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMMS19 antibody\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cspan style=\"font-weight: 400;\"\u003eSTATEMENT\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eManuals on the web are for your reference only, specifications are subject to the delivery manuals.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-weight: 400;\"\u003eFEATURED PRODUCT\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cbr\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":42429880729824,"sku":"FNab05249","price":330.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/fine_test_logo_b9d627a3-efaa-465a-9c19-d2eaf31a8e3a.jpg?v=1645519057","url":"https:\/\/rndmate.com\/products\/anti-mms19-antibody-fnab05249","provider":"알앤디메이트","version":"1.0","type":"link"}