{"product_id":"anti-rffl-antibody-fnab07252","title":"anti- RFFL antibody","description":"\u003cp\u003eanti- RFFL antibody\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eProduct Name\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eRFFL antibody\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e100µg\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eliquid\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eImmunogen affinity purified\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e≥95% as determined by SDS-PAGE\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eRabbit\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003epolyclonal\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIgG\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBACKGROUND\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eE3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Mediates 'Lys-48'-linked polyubiquitination of PRR5L and its subsequent proteasomal degradation thereby indirectly regulating cell migration through the mTORC2 complex. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. Negatively regulates the tumor necrosis factor-mediated signaling pathway through targeting of RIPK1 to ubiquitin-mediated proteasomal degradation. Negatively regulates p53\/TP53 through its direct ubiquitination and targeting to proteasomal degradation. Indirectly, may also negatively regulate p53\/TP53 through ubiquitination and degradation of SFN. May also play a role in endocytic recycling.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMMUNOGEN INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ering finger and FYVE-like domain containing 1\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eRNF189, RNF34L\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e37-41 kDa\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAPPLICATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eELISA, WB\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eRecommended Dilution\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWB: 1:500-1:2000\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUNIPROT INFORMATION\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/Q8WZ73\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eQ8WZ73\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIMAGES\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg class=\"mx-auto\" alt=\"\" src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab07252.jpg\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003emouse testis tissue were subjected to SDS PAGE followed by western blot with FNab07252(RFFL antibody) at dilution of 1:500\u003c\/span\u003e\u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg","offer_id":42429929750752,"sku":"FNab07252","price":310.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/fine_test_logo_00de1b51-581a-4909-8cfb-bf90906d3377.jpg?v=1645516813","url":"https:\/\/rndmate.com\/products\/anti-rffl-antibody-fnab07252","provider":"알앤디메이트","version":"1.0","type":"link"}