{"product_id":"bcl-3-polyclonal-antibody-bt-lab","title":"Bcl-3 Polyclonal Antibody","description":"\u003cp\u003eThis gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.The Bcl-3 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Bcl-3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Bcl-3 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe Bcl-3 protein is a member of the IκB family of proteins and plays a crucial role in the regulation of the NF-κB signaling pathway. Aberrant expression of Bcl-3 has been implicated in various diseases, including cancer, inflammation, and autoimmune disorders. Therefore, the Bcl-3 Polyclonal Antibody is an essential tool for researchers studying the role of Bcl-3 in these diseases.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThis antibody has been validated for its specificity and sensitivity in various cell lines and tissues, including human, mouse, and rat. It recognizes a single band of approximately 70 kDa in Western blot analysis and shows strong staining in the nucleus of cells in immunohistochemistry and immunofluorescence assays.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eIn summary, the Bcl-3 Polyclonal Antibody is a reliable and high-quality antibody that can be used for the detection of Bcl-3 protein in various biological samples. Its specificity and sensitivity make it an essential tool for researchers studying the role of Bcl-3 in various diseases.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42358951313632,"sku":"BT-AP06713","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_a995d181-bbd7-4f32-99ce-d6fa76e27f4b.png?v=1644563873","url":"https:\/\/rndmate.com\/products\/bcl-3-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}