{"product_id":"c-myc-phospho-thr358-polyclonal-antibody-bt-lab","title":"c-Myc(Phospho Thr358) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.\u003c\/p\u003e\n\u003cp\u003eThe c-Myc(Phospho Thr358) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated c-Myc at threonine 358 residue. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eThe c-Myc protein plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Phosphorylation of c-Myc at threonine 358 has been implicated in the regulation of its transcriptional activity and stability. Therefore, the ability to accurately detect and quantify phosphorylated c-Myc at this specific site is of utmost importance in understanding the intricate mechanisms underlying cellular signaling pathways.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody exhibits exceptional specificity towards phosphorylated c-Myc at threonine 358, enabling precise and reliable detection in various experimental settings. It has been extensively validated using a range of techniques, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring its suitability for diverse applications.\u003cbr\u003e\u003cbr\u003eThe c-Myc(Phospho Thr358) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its high affinity and sensitivity allow for the detection of even low levels of phosphorylated c-Myc, facilitating accurate quantification and analysis.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the c-Myc(Phospho Thr358) Polyclonal Antibody is an indispensable tool for researchers and scientists studying the intricate mechanisms of cellular signaling pathways and their implications in various diseases and disorders.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42358957277408,"sku":"BT-AP06915","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_5d64bb9f-54c8-4fc0-8372-c61df54c0ef9.png?v=1644569132","url":"https:\/\/rndmate.com\/products\/c-myc-phospho-thr358-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}