{"product_id":"cd59-polyclonal-antibody-bt-lab","title":"CD59 Polyclonal Antibody","description":"\u003cp\u003eCD59 encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. CD59 glycoprotein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and\/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.\u003c\/p\u003e\n\u003cp\u003eThe CD59 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CD59 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CD59 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CD59 protein, making it an ideal tool for various research applications.\u003cbr\u003e\u003cbr\u003eThe CD59 protein is a glycosylphosphatidylinositol (GPI)-anchored protein that plays a crucial role in the regulation of complement activation and membrane attack complex (MAC) formation. Dysregulation of CD59 expression has been implicated in various pathological conditions, including autoimmune diseases, cancer, and infectious diseases. Therefore, the CD59 Polyclonal Antibody can be used to investigate the expression and function of CD59 protein in various biological systems.\u003cbr\u003e\u003cbr\u003eThe CD59 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a CD59 peptide column. The antibody is provided in a liquid form, which can be easily diluted and used for various applications, including Western blotting, immunohistochemistry, and flow cytometry. The antibody has been validated for its specificity and sensitivity using various biological samples, including human cell lines and tissues.\u003cbr\u003e\u003cbr\u003eIn summary, the CD59 Polyclonal Antibody is a reliable and high-quality immunological reagent that can be used for the detection and quantification of CD59 protein in various biological samples. Its high specificity and sensitivity make it an ideal tool for investigating the role of CD59 protein in various pathological conditions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42357793882336,"sku":"BT-AP01520","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_b2e9bf1d-110d-4ca8-b7b1-7f45734d841b.png?v=1644579193","url":"https:\/\/rndmate.com\/products\/cd59-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}