{"product_id":"cdc23-polyclonal-antibody-bt-lab","title":"Cdc23 Polyclonal Antibody","description":"\u003cp\u003eCell division cycle 23 encoded by CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2\/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.\u003c\/p\u003e\n\u003cp\u003eThe Cdc23 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cdc23 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cdc23 protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunoprecipitation, and immunofluorescence assays.\u003cbr\u003e\u003cbr\u003eThe Cdc23 protein is a key component of the anaphase-promoting complex\/cyclosome (APC\/C), which is a large multi-subunit E3 ubiquitin ligase that regulates cell cycle progression and mitotic exit. The Cdc23 protein plays a critical role in the activation of the APC\/C and the subsequent degradation of key cell cycle regulators, such as cyclin B and securin. Dysregulation of the APC\/C-Cdc23 pathway has been implicated in various human diseases, including cancer and neurodegenerative disorders.\u003cbr\u003e\u003cbr\u003eThe Cdc23 Polyclonal Antibody is an essential tool for researchers studying the role of the APC\/C-Cdc23 pathway in cell cycle regulation and disease pathogenesis. This antibody is available in various sizes and formats to suit different experimental needs. It is recommended for use in a variety of applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. With its high specificity and sensitivity, the Cdc23 Polyclonal Antibody is a reliable and valuable reagent for any research project involving the APC\/C-Cdc23 pathway.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42357798797536,"sku":"BT-AP01574","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_1d39488d-2377-495b-8883-d17b54001c6a.png?v=1644579050","url":"https:\/\/rndmate.com\/products\/cdc23-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}