{"product_id":"col18a1-polyclonal-antibody-bt-lab","title":"COL18A1 Polyclonal Antibody","description":"\u003cp\u003eCOL18A1 (collagen type XVIII alpha 1 chain) encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in COL18A1 are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe COL18A1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of COL18A1 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards COL18A1. \u003cbr\u003e\u003cbr\u003eCOL18A1, also known as collagen type XVIII alpha 1 chain, is a crucial component of the extracellular matrix and plays a significant role in tissue development and maintenance. Dysregulation of COL18A1 has been implicated in various pathological conditions, including cancer and vascular diseases. Therefore, the accurate detection and quantification of COL18A1 expression are of utmost importance in understanding its functional significance and potential therapeutic implications.\u003cbr\u003e\u003cbr\u003eThe COL18A1 Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated in multiple experimental settings, ensuring reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and optimal performance. It is supplied as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution.\u003cbr\u003e\u003cbr\u003eIn summary, the COL18A1 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of COL18A1 protein expression. Its exceptional sensitivity and versatility make it an invaluable asset for researchers and clinicians studying the role of COL18A1 in various biological processes and diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42357830156512,"sku":"BT-AP02071","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_9c5536ff-08e9-4ba0-9fb4-f06f1fa87ddf.png?v=1644578816","url":"https:\/\/rndmate.com\/products\/col18a1-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}