{"product_id":"eif3l-polyclonal-antibody-bt-lab","title":"eIF3L Polyclonal Antibody","description":"\u003cp\u003eComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.\u003c\/p\u003e\n\u003cp\u003eThe eIF3L Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of eIF3L protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein. \u003cbr\u003e\u003cbr\u003eeIF3L, also known as eukaryotic translation initiation factor 3 subunit L, plays a crucial role in the initiation of protein synthesis. It is involved in the assembly of the eIF3 complex, which is essential for the recognition of the mRNA start codon and subsequent ribosome recruitment. Dysregulation of eIF3L expression has been implicated in various diseases, including cancer and neurodegenerative disorders. \u003cbr\u003e\u003cbr\u003eThe eIF3L Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of eIF3L protein levels in different sample types. \u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The eIF3L Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent and reproducible results. \u003cbr\u003e\u003cbr\u003eIn summary, the eIF3L Polyclonal Antibody is a valuable tool for researchers studying protein synthesis and its regulation. Its high specificity, sensitivity, and versatility make it an ideal choice for various applications in both basic and clinical research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42357891170528,"sku":"BT-AP02893","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_dcf2af0c-fadd-4292-a127-2b56e4cfeb8d.png?v=1644578769","url":"https:\/\/rndmate.com\/products\/eif3l-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}