{"product_id":"f43338-0-4ml","title":"RIPK1 Antibody","description":"\u003cp\u003eEssential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses. Upon TNFA stimulation RIPK1 is recruited to a TRADD-TRAF complex initiated by TNFR1 trimerization. There, it is ubiquitinated via 'Lys-63'-link chains, inducing its association with the IKK complex, and its activation through NEMO binding of polyubiquitin chains.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":46768901587168,"sku":"F43338-0.4ML","price":429.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_d7332184-6f4e-4f99-b4b1-0c9756f4a25c.jpg?v=1734506623","url":"https:\/\/rndmate.com\/products\/f43338-0-4ml","provider":"알앤디메이트","version":"1.0","type":"link"}