{"product_id":"f49682-0-08ml","title":"VHL Antibody","description":"\u003cp\u003eVon Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of VHL gene is the basis of familial inheritance of VHL syndrome. The protein is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G\/RPB7 is also reported to be a target of this protein.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.08 ml \/ Rabbit","offer_id":46768768844000,"sku":"F49682-0.08ML","price":199.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_a8c06e41-2463-40be-ba8b-e6a0422ca7a6.jpg?v=1734500631","url":"https:\/\/rndmate.com\/products\/f49682-0-08ml","provider":"알앤디메이트","version":"1.0","type":"link"}