{"product_id":"f52344-0-08ml","title":"SUMO2 Antibody","description":"\u003cp\u003eUbiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.08 ml \/ Mouse","offer_id":46768677519584,"sku":"F52344-0.08ML","price":199.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_c943bf71-abf4-42c6-b8b0-5578d793b90d.jpg?v=1734497135","url":"https:\/\/rndmate.com\/products\/f52344-0-08ml","provider":"알앤디메이트","version":"1.0","type":"link"}