{"product_id":"f54141-0-2ml","title":"Dnmt3a Antibody","description":"\u003cp\u003eRequired for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.2 ml \/ Mouse","offer_id":46768612114656,"sku":"F54141-0.2ML","price":429.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_2f1d6591-bf1c-4c78-8b8f-fce2f20548be.jpg?v=1734493202","url":"https:\/\/rndmate.com\/products\/f54141-0-2ml","provider":"알앤디메이트","version":"1.0","type":"link"}