{"product_id":"fgfr-4-polyclonal-antibody-bt-lab","title":"FGFR-4 Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by FGFR4 (fibroblast growth factor receptor 4) is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of FGFR4, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.\u003c\/p\u003e\n\u003cp\u003eThe FGFR-4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of FGFR-4 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring high quality and reliability in experimental results.\u003cbr\u003e\u003cbr\u003eThe FGFR-4 Polyclonal Antibody exhibits exceptional affinity and specificity towards the FGFR-4 protein, making it an ideal choice for researchers and scientists working in the field of cancer biology, developmental biology, and signal transduction pathways. It enables the investigation of FGFR-4 protein expression levels, localization, and functional studies in a wide range of experimental settings.\u003cbr\u003e\u003cbr\u003eThis antibody is validated for use in various applications, including Western blotting, immunohistochemistry, immunofluorescence, and flow cytometry. It has been extensively tested and proven to provide consistent and reproducible results across different sample types and species.\u003cbr\u003e\u003cbr\u003eThe FGFR-4 Polyclonal Antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reliability. It is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and versatility, the FGFR-4 Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying FGFR-4 protein function and its role in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42357916991712,"sku":"BT-AP03226","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_10d3341a-ae8d-4752-9e4a-eb90edf4f934.png?v=1644570694","url":"https:\/\/rndmate.com\/products\/fgfr-4-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}