{"product_id":"fy-ig0032-100","title":"NF κB P105P50 Mouse Monoclonal Antibody(4D11)","description":"\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e WB 1:500-1,000\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous NF κB P105\/P50 proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e NFKB1,nuclear factor nf-kappa-b p105,DNA-binding factor KBF1\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e Nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines,oxidant-free radicals,ultraviolet irradiation,and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e WB\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 50,110KD\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e 50,110KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e P19838\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0032\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e NF κB P105P50 Mouse Monoclonal Antibody(4D11)\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['50', '100']","brand":"Feiyuebio","offers":[{"title":"100","offer_id":47495699267808,"sku":"FY-IG0032-100","price":0.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/Feiyuebio_d361896a-dca4-4813-ba82-e955ddaf0938.png?v=1749882243","url":"https:\/\/rndmate.com\/products\/fy-ig0032-100","provider":"알앤디메이트","version":"1.0","type":"link"}