{"product_id":"glur-2-polyclonal-antibody-bt-lab","title":"GluR-2 Polyclonal Antibody","description":"\u003cp\u003eGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Glutamate receptor 2 belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG-\u0026gt;CGG; Q-\u0026gt;R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q\/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.\u003c\/p\u003e\n\u003cp\u003eThe GluR-2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of GluR-2 protein expression in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers in the field of neuroscience.\u003cbr\u003e\u003cbr\u003eThe GluR-2 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested for its ability to recognize GluR-2 in a variety of experimental conditions, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eWith its superior performance, this antibody enables accurate and reproducible quantification of GluR-2 protein levels, facilitating in-depth investigations into the role of GluR-2 in synaptic plasticity, neuronal development, and neurological disorders. Its specificity towards GluR-2 ensures minimal cross-reactivity with other glutamate receptor subunits, enhancing the reliability of experimental results.\u003cbr\u003e\u003cbr\u003eThe GluR-2 Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into existing laboratory protocols. It is provided in a liquid formulation, eliminating the need for reconstitution and minimizing the risk of sample contamination. The antibody is also available in different sizes to accommodate various experimental needs.\u003cbr\u003e\u003cbr\u003eIn summary, the GluR-2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of GluR-2 protein expression. Its exceptional sensitivity, specificity, and ease of use make it an invaluable asset for researchers studying the intricate mechanisms of synaptic transmission and neurological disorders.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42357941371104,"sku":"BT-AP03597","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_455929e9-0ec8-4d62-a320-b6ca33544af6.png?v=1644577469","url":"https:\/\/rndmate.com\/products\/glur-2-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}