{"product_id":"grf-1-phospho-tyr1105-polyclonal-antibody-bt-lab","title":"GRF-1(Phospho Tyr1105) Polyclonal Antibody","description":"\u003cp\u003eThe human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.\u003c\/p\u003e\n\u003cp\u003eThe GRF-1(Phospho Tyr1105) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GRF-1 protein phosphorylated at Tyr1105 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eGRF-1, also known as growth factor receptor-bound protein 2 (Grb2)-related protein 1, plays a crucial role in various cellular processes, including cell growth, differentiation, and signal transduction. Phosphorylation of GRF-1 at Tyr1105 residue is known to regulate its function and interaction with other signaling molecules.\u003cbr\u003e\u003cbr\u003eThe GRF-1(Phospho Tyr1105) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated GRF-1 in complex biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured using high-quality materials and stringent quality control measures to ensure consistent and reproducible results. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation steps.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the GRF-1(Phospho Tyr1105) Polyclonal Antibody is an indispensable tool for researchers studying GRF-1 signaling pathways and its role in various physiological and pathological conditions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42359064887520,"sku":"BT-AP15780","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_2fa526a8-a156-447d-8a10-9764207fc3da.png?v=1644571437","url":"https:\/\/rndmate.com\/products\/grf-1-phospho-tyr1105-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}