{"product_id":"hecw1-polyclonal-antibody-bt-lab","title":"HECW1 Polyclonal Antibody","description":"\u003cp\u003eE3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway:Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,Contains 2 WW domains.,subunit:Interacts with DVL1 and SSR3. Also interacts with mutant SOD1.,tissue specificity:Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.,\u003c\/p\u003e\n\u003cp\u003eThe HECW1 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in a wide range of research applications. This antibody has been raised against a specific antigen and has been extensively validated for its specificity and sensitivity. It is a polyclonal antibody, which means that it is produced by multiple B cells and recognizes multiple epitopes on the target antigen.\u003c\/p\u003e\n\u003cp\u003eThis results in a highly sensitive and specific antibody that can be used for a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. The HECW1 Polyclonal Antibody is supplied in a convenient format and is ready to use in a variety of applications. It is an essential tool for researchers who are studying the function and regulation of HECW1 in various biological processes. With its high specificity and sensitivity, this antibody is an ideal choice for researchers who require reliable and reproducible results.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42359073177824,"sku":"BT-AP09859","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_f79482d0-277d-4d25-9323-25d2ab48a978.png?v=1644578062","url":"https:\/\/rndmate.com\/products\/hecw1-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}