{"product_id":"iκb-alpha-phospho-tyr42-polyclonal-antibody-bt-lab","title":"IκB-alpha(Phospho Tyr42) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B\/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.\u003c\/p\u003e\n\u003cp\u003eThe IκB-alpha(Phospho Tyr42) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of IκB-alpha protein phosphorylated at Tyr42. This antibody has been rigorously validated for use in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.\u003cbr\u003e\u003cbr\u003eIκB-alpha is a key regulator of the nuclear factor kappa B (NF-κB) signaling pathway, which plays a critical role in the regulation of immune responses, inflammation, and cell survival. Phosphorylation of IκB-alpha at Tyr42 is known to modulate its function and stability, thereby influencing NF-κB activation.\u003cbr\u003e\u003cbr\u003eThe IκB-alpha(Phospho Tyr42) Polyclonal Antibody has been developed using state-of-the-art techniques to ensure high specificity and sensitivity. It has been extensively tested and validated to provide reliable and reproducible results. This antibody exhibits minimal cross-reactivity with non-phosphorylated IκB-alpha and other related proteins, ensuring accurate detection and quantification of phosphorylated IκB-alpha.\u003cbr\u003e\u003cbr\u003eWith its superior performance and versatility, the IκB-alpha(Phospho Tyr42) Polyclonal Antibody is an indispensable tool for researchers studying the NF-κB signaling pathway and its role in various biological processes. Its high affinity and specificity make it ideal for both qualitative and quantitative analysis of phosphorylated IκB-alpha in various sample types, including cell lysates, tissue extracts, and cultured cells.\u003cbr\u003e\u003cbr\u003eOrder the IκB-alpha(Phospho Tyr42) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of NF-κB signaling and its implications in disease pathogenesis.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42359103357152,"sku":"BT-AP10542","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_534db66d-1f29-48cf-8a48-270b8d7db3a6.png?v=1644566506","url":"https:\/\/rndmate.com\/products\/i%ce%bab-alpha-phospho-tyr42-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}