{"product_id":"il-1rii-polyclonal-antibody-bt-lab","title":"IL-1RII Polyclonal Antibody","description":"\u003cp\u003eInterleukin-1 receptor type 2 encoded by IL1R2 is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1\/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.\u003c\/p\u003e\n\u003cp\u003eThe IL-1RII Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Interleukin-1 Receptor Type II (IL-1RII) protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.\u003cbr\u003e\u003cbr\u003eIL-1RII is a crucial component of the interleukin-1 signaling pathway, playing a significant role in modulating the immune response and inflammation. By binding to IL-1 cytokines, IL-1RII acts as a decoy receptor, preventing the activation of downstream signaling cascades. Therefore, accurate measurement of IL-1RII expression levels is essential for understanding the intricate mechanisms underlying immune regulation and inflammatory processes.\u003cbr\u003e\u003cbr\u003eThe IL-1RII Polyclonal Antibody exhibits exceptional specificity, displaying minimal cross-reactivity with other related proteins. This feature guarantees reliable and precise results, enabling researchers to confidently analyze IL-1RII expression in complex biological matrices. Furthermore, the antibody demonstrates high sensitivity, allowing for the detection of low levels of IL-1RII protein, even in samples with limited availability.\u003cbr\u003e\u003cbr\u003eThis antibody is suitable for various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA). Its versatility enables researchers to explore IL-1RII expression patterns in different tissues, cell lines, and experimental models. Additionally, the antibody is compatible with a wide range of species, facilitating comparative studies across various organisms.\u003cbr\u003e\u003cbr\u003eThe IL-1RII Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming reconstitution steps. The antibody is also available in different sizes, allowing researchers to choose the most suitable option based on their experimental requirements.\u003cbr\u003e\u003cbr\u003eIn summary, the IL-1RII Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of IL-1RII protein. Its exceptional specificity, sensitivity, and compatibility make it an invaluable asset for researchers studying immune regulation, inflammation, and related fields.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42358205743328,"sku":"BT-AP07435","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_1ec6d9d6-8c9a-4378-940d-f53d72383214.png?v=1644576414","url":"https:\/\/rndmate.com\/products\/il-1rii-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}