{"product_id":"nephrocystin-5-polyclonal-antibody-bt-lab","title":"Nephrocystin-5 Polyclonal Antibody","description":"\u003cp\u003eIQCB1 encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQ calmodulin-binding motif-containing protein 1 has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQ calmodulin-binding motif-containing protein 1 is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.\u003c\/p\u003e\n\u003cp\u003eThe Nephrocystin-5 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Nephrocystin-5 protein expression in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eNephrocystin-5, also known as NPHP5, is a crucial protein involved in the regulation of ciliary function and maintenance of renal tubular integrity. Dysregulation or mutations in Nephrocystin-5 have been associated with various renal disorders, including nephronophthisis, a genetic kidney disease characterized by cyst formation and progressive renal failure.\u003cbr\u003e\u003cbr\u003eThe Nephrocystin-5 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to Nephrocystin-5 protein without cross-reactivity to other related proteins. This high specificity enables accurate and reliable detection of Nephrocystin-5 expression in complex biological samples, such as tissue lysates or cell extracts.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody demonstrates remarkable sensitivity, allowing for the detection of low levels of Nephrocystin-5 protein expression. This attribute is particularly advantageous when studying samples with limited protein availability or low expression levels.\u003cbr\u003e\u003cbr\u003eThe Nephrocystin-5 Polyclonal Antibody has been extensively validated through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. These validation studies have consistently demonstrated the antibody's ability to specifically detect Nephrocystin-5 protein in different sample types, ensuring accurate and reproducible results.\u003cbr\u003e\u003cbr\u003eIn summary, the Nephrocystin-5 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of Nephrocystin-5 protein expression. Its exceptional specificity, sensitivity, and validated performance make it an invaluable asset for researchers and clinicians studying renal disorders and related pathologies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42358120055008,"sku":"BT-AP05890","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_c1d8981e-fad7-4250-bee8-b9ab7ef4f19b.png?v=1644576352","url":"https:\/\/rndmate.com\/products\/nephrocystin-5-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}