{"product_id":"new-product-394232","title":"GFRα-1 (K90) polyclonal antibody","description":"\u003cp\u003eGlial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. GDNF is a glycosylated, disulfide-bonded homodimer that is distantly related to the TGFβ superfamily of growth factors. Three receptors for these factors, GFRα-1 (also designated GDNFR-α, RETL1 or TrnR-1), GFRα-2 (also designated GDNFR-β, RETL2, NTNR-α or TrnR-2) and GFRα-3 have been identified. The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosyl-phosphoinositol linkage. Both GFRα-1 and GFRα-2 have been shown to mediate the GDNF-dependent and NTN-dependent phosphorylation and activation of the tyrosine kinase Ret. GFRα-3 is expressed only during development.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44091992539360,"sku":"BS1141","price":325.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_e1b71ddd-cfc9-4cca-8dc2-6b786773b61b.png?v=1689710151","url":"https:\/\/rndmate.com\/products\/new-product-394232","provider":"알앤디메이트","version":"1.0","type":"link"}