{"product_id":"new-product-395008","title":"14-3-3 θ (Q67) polyclonal antibody","description":"\u003cp\u003eProtein interactions with 14-3-3 show distinct preferences for it’s different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 tau\/theta is primarily expressed in T-cells although it occurs at lower levels in the brain, heart, pancreas placenta and kidneys. It plays a role in cell cycle progression via interaction with p27(Kip1). Along with COPI, the theta isoform binds the GB1 RSR sequence involved in protein trafficking. The isoform forms a complex with Hsp60 and cellular prion protein which may be involved in prion diseases. Elevated levels of 14-3-3 tau\/theta are observed in amyotrophic lateral sclerosis. 14-3-3 tau\/theta also binds BCR\/Abl, bacterial effector protein Tir, yes-associated protein and the FSH receptor.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":44092041527520,"sku":"BS2179","price":325.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_6b8e236b-60d7-4191-9d36-9d1d12adeaad.png?v=1689711916","url":"https:\/\/rndmate.com\/products\/new-product-395008","provider":"알앤디메이트","version":"1.0","type":"link"}