{"product_id":"new-product-395487","title":"TIS11B (D88) polyclonal antibody","description":"\u003cp\u003eTIS11B (tetradecanoyl phorbol acetate-inducible sequence 11b), also known as ZFP36L1, BRF1 (butyrate response factor 1), ERF1 (EGF response factor 1), cMG1, Berg36 or RNF162B, is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating Cys-His motif. TIS11B is an mRNA binding protein and is known to interact with the 3'-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092068626656,"sku":"BS3004","price":325.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_4bf26b60-59e1-4ec8-99d6-0f79d198c447.png?v=1689712967","url":"https:\/\/rndmate.com\/products\/new-product-395487","provider":"알앤디메이트","version":"1.0","type":"link"}