{"product_id":"new-product-396368","title":"LATS1 polyclonal antibody","description":"\u003cp\u003eThe Drosophila tumor suppressor protein lats (for large tumor suppressor) is a putative protein kinase that shares homology with three proteins in Neurospora and budding yeast that are involved in cell cycle and growth regulation: S. cerevisiae Dbf2 and Dbf20, and Neurospora cot-1. Mosaic screens in Drosophila have identified the lats gene as a tumor suppressor in this species. The human homolog, designated LATS1, was shown to inhibit tumor growth in lats-deficient Drosophila. Human LATS1 binds to Cdc2 in early mitosis and appears to negatively regulate the kinase activity of Cdc2. LATS1-deficient mice are highly sensitive to carcinogenic treatments and develop soft-tissue sarcomas and ovarian stromal cell tumors, indicating a role for mammalian LATS1 in tumorigenesis.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092153888992,"sku":"BS60042","price":325.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_09ec9b5a-f640-41c9-bf11-a8aa3f3999ec.png?v=1689716098","url":"https:\/\/rndmate.com\/products\/new-product-396368","provider":"알앤디메이트","version":"1.0","type":"link"}