{"product_id":"new-product-396865","title":"HSD17B4 polyclonal antibody","description":"\u003cp\u003e17β-HSD4 (17β-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme\/protein 2 (MFE-2\/MFP-2), D-bifunctional enzyme or 17-β Estradiol 17β-HSD4 (17β-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme\/protein 2 (MFE-2\/MFP-2), D-bifunctional enzyme or 17-β Estradiol dehydrogenase type IV. It belongs to the 17β-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17β-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol β-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17β-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17β-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092184658144,"sku":"BS60710","price":325.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_b13695ca-f924-4619-8b84-e9868407b3a2.png?v=1689717394","url":"https:\/\/rndmate.com\/products\/new-product-396865","provider":"알앤디메이트","version":"1.0","type":"link"}