{"product_id":"new-product-396889","title":"ITIH4 polyclonal antibody","description":"\u003cp\u003eThe inter-α-trypsin inhibitor (ITI) family is a group of structurally related plasma serine protease inhibitors synthesized in the liver and built up from different combinations of three highly homologous heavy chains (ITI-HI, ITI-H2 and ITI-H3) and one light chain (Bikunin). Another member of the ITI family, ITI-H4, harbors a proline-rich region (PRR) in its C-terminus. ITI is a glycoprotein composed of three polypeptides linked by chondroitin sulphate: two heavy chains, ITI-H1 and ITI-H2, and Bikunin. Bikunin confers the protease-inhibitor function of ITI. The heavy chains of the ITI family, designated as SHAPs (for serum-derived hyaluronan-associated proteins), bind covalently to hyaluronic acid (HA), resulting in pericellular matrix stabilization. While the ITI family is primarily composed of multi-polypeptide molecules, ITI-H4 is a single chain molecule. Unlike other ITI family members, the gene transcriptions and products for rat and human ITI-H4 demonstrate marked differences, suggesting possible species-specific functions for ITI-H4. The gene encoding human ITI-H4 maps to chromosome 3p21.1.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092185805024,"sku":"BS60746","price":325.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_230d2a24-792a-4e26-a291-d0e947f3a686.png?v=1689717457","url":"https:\/\/rndmate.com\/products\/new-product-396889","provider":"알앤디메이트","version":"1.0","type":"link"}