{"product_id":"new-product-397777","title":"ZNT8 polyclonal antibody","description":"\u003cp\u003eZinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions (such as neuroregulation) and acts as a cofactor for numerous enzymes and transcription factors. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members commonly contain six membrane-spanning domains, a large histidine-rich intracellular loop and a C-terminal tail. ZnT-8 (zinc transporter 8), also known as SLC30A8 (solute carrier family 30 member 8), is a 369 amino acid multi-pass membrane protein that belongs to the ZnT family and is a major autoantigen in type I diabetes. Expressed specifically in pancreas islet cells, ZnT-8 functions as a zinc-efflux transporter that facilitates the accumulation of zinc in intracellular vesicles and is essential for the zinc-dependent maturation of Insulin within pancreatic cells. Multiple isoforms of ZnT-8 exist due to alternative splicing events.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Rat","offer_id":44092235022560,"sku":"BS62515","price":325.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_21dd2d9e-ec16-46e6-a268-f8fefc827a1d.png?v=1689719793","url":"https:\/\/rndmate.com\/products\/new-product-397777","provider":"알앤디메이트","version":"1.0","type":"link"}