{"product_id":"new-product-399522","title":"Cdk1\/Cdc2 (phospho-T14) polyclonal antibody","description":"\u003cp\u003eCdc2, an evolutionarily conserved serine\/threonine-specific protein kinase, is essential in the cell cycle transition from G2 to M phase. Cdc2 is regulated by association with B-type cyclins and by reversible phosophorylation. Cyclin B binding facilitates the phosphorylation of Cdc2 p34 on three regulatory sites: threonine 14, tyrosine 15, and threonine 161. In higher eukaryotes, Cdc2 is negatively regulated by phosphorylation of two residues located in the ATP-binding site, Thr 14 and Tyr 15. Cdc2 is positively regulated by the cyclin-dependent phosphorylation of Thr 161. Both phosphorylation and de- phosphorylation at Thr 161 are required for progression through the cell cycle.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092111651040,"sku":"BS4265","price":348.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_2ba7f1a9-3ce3-462e-aa60-7498a06e65b9.png?v=1689714542","url":"https:\/\/rndmate.com\/products\/new-product-399522","provider":"알앤디메이트","version":"1.0","type":"link"}