{"product_id":"new-product-399573","title":"Catenin-δ1 (phospho-Y228) polyclonal antibody","description":"\u003cp\u003eCatenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion. Catenin δ-1 has both positive and negative effects on cadherin-mediated adhesion. Actin dynamics are also regulated by catenin δ-1, which modulates RhoA, Rac, and cdc42 proteins. Analogous to β-catenin, catenin δ-1 translocates to the nucleus, although its role at this location is unclear. Many studies show that catenin δ-1 is expressed irregularly or is absent in various types of tumor cells, suggesting that catenin δ-1 may function as a tumor suppressor.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092113977568,"sku":"BS4381","price":348.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_929c0d00-6b86-4956-88dc-2dceb147c1a6.png?v=1689714703","url":"https:\/\/rndmate.com\/products\/new-product-399573","provider":"알앤디메이트","version":"1.0","type":"link"}