{"product_id":"new-product-399790","title":"Catenin-β (phospho-S33\/S37\/T41) polyclonal antibody","description":"\u003cp\u003eβ-Catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. CK1 phosphorylates β-catenin at Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3β. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092130230496,"sku":"BS5056","price":348.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_732cdbec-ce54-4af4-905b-3f0a1d7fab57.png?v=1689715181","url":"https:\/\/rndmate.com\/products\/new-product-399790","provider":"알앤디메이트","version":"1.0","type":"link"}