{"product_id":"new-product-399831","title":"Bim (phospho-S69\/S65) polyclonal antibody","description":"\u003cp\u003ePro-apototic Bcl-2 family members promote cell death by neutralizing their anti-apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins, and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long). ERK1\/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1\/2 phosphorylation exist on BimEL, whereas ERK1\/2 does not effect BimS and BimL, implying a unique role for BimEL in cell survival signaling.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092244132064,"sku":"BS64039","price":348.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_e62fd8ae-ffab-4e76-be26-419704940fd1.png?v=1689720177","url":"https:\/\/rndmate.com\/products\/new-product-399831","provider":"알앤디메이트","version":"1.0","type":"link"}