{"product_id":"new-product-400189","title":"TAL1 (Acetyl-K221\/K222) polyclonal antibody","description":"\u003cp\u003eActivation of TAL1 characterizes up to 60% ofcases of human T cell acute lymph oblastic leukemia,making it themost frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phospho protein and basic helixx-loop-helixtranscription factorknown to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB\/HTF4 to a nucleotide sequence motif termed the E-box.In addition, leukemogenesisis accelerated dramatically bytransgenic coexpression of TAL1 and the catalyticsubunit ofcasein kinase IIα, a serine\/threonine protein kinase known tomodulate the activity of other βHLH transcription factors.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092244623584,"sku":"BS64094","price":408.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_6cc73856-789a-451d-8a39-1d695aaf5279.png?v=1689720202","url":"https:\/\/rndmate.com\/products\/new-product-400189","provider":"알앤디메이트","version":"1.0","type":"link"}