{"product_id":"new-product-400873","title":"CREB3 polyclonal antibody","description":"\u003cp\u003eHCF-1 is a cellular protein required by VP16, a viral tegument, to activate the herpes simplex virus (HSV) immediate-early genes. In addition to playing an essential role in cell proliferation, HCF-1 also functions as a coactivator for the basic leucine zipper transcription factor LZIP (also designated Luman or CREB3 . Both LZIP and VP16 contain the binding motif (D\/E) HXY (S\/A), which is recognized by an amino terminal beta-propeller domain in HCF-1. LZIP, a member of the ATF\/CREB family, is a type II membrane-associated glycoprotein that is ubiquitously expressed in adult and fetal tissues. LZIP associates with the endoplasmic reticulum, where it sequesters most of the cellular HCF-1. Like other CREB\/ATF family members, LZIP activates transcription from genes containing cyclic AMP response elements (CREs) . LZIP activity is repressed by the inhibitory interaction of HCLP-1 .\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":44092320252128,"sku":"BS6947","price":408.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_556f9cf8-b141-4d45-8add-9fb7d8a753f6.png?v=1689724427","url":"https:\/\/rndmate.com\/products\/new-product-400873","provider":"알앤디메이트","version":"1.0","type":"link"}