{"product_id":"new-product-401318","title":"CRLF2 polyclonal antibody","description":"\u003cp\u003eThe gene encoding murine TSLP maps to chromosome 18. Its human homologue is expressed in several tissues, including heart, liver and prostate. TSLP mediates its function by binding to a receptor complex: first binding with low affinity to a TSLP-specific chain designated TSLPR, (also designated CRLF2, cytokine receptor-like factor 2), then forming a high affinity complex with the IL-7Ra subunit, which explains the overlapping biological properties between TSLP and IL-7. Both TSLP and IL-7 induce phosphorylation of the transcription factor Stat5, but unlike IL-7, TSLP-mediated signaling does not activate the JAKs. TSLP prevents apoptosis and stimulates the proliferation of myeloid cells, which is supported by the coexpression of TSLPR and IL-7Ra on monocytes and dendritic cells.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092355477728,"sku":"BS70875","price":408.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_36b254d5-c5df-412b-aec8-231770447444.png?v=1689725577","url":"https:\/\/rndmate.com\/products\/new-product-401318","provider":"알앤디메이트","version":"1.0","type":"link"}