{"product_id":"new-product-403858","title":"HBB polyclonal antibody","description":"\u003cp\u003eHemoglobin (Hgb) is coupled to four iron-binding,methene-linked tetrapyrrole rings(heme). The α (16p13.3; 5'-ζ-pseudoζ-pseudoα2-pseudoα1-α2-α1-θ1-3') and β (11p15.4) globin loci determine the basic hemoglobin structure.The globin portion of Hgb consists of twoαchains and two β chains arranged in pairsforming a tetramer. Each of the four globin chainscovalently associates with a heme group. The bonds between α and β chains are weaker than between similar globin chains, therebyforming a cleavage plane that is important for oxygen binding and release. High affinityfor oxygen occurs upon relaxation of theα1-β2 cleavage plane. When the twoα1-β2 interfaces are closely bound, hemoglobin has a lowaffinityfor oxygen. Hb A,which containstwo α chains plustwo β chains,comprises 97% of totalcirculating\u003cbr\u003e\nhemoglobin. The remaining 3% of totalcirculating hemoglobin iscomprised of Hb A-2,which consists of twoαchains plustwo δ chains, and fetal hemoglobin (Hb F),which consists of two α chainstogetherwith two γ chains.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":44092481175776,"sku":"BS8007","price":408.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_f0b5dd2e-8234-4fae-bb65-ec6a9b5f6b44.png?v=1689731636","url":"https:\/\/rndmate.com\/products\/new-product-403858","provider":"알앤디메이트","version":"1.0","type":"link"}