{"product_id":"new-product-407177","title":"phospho-AKT3 (Ser472) Polyclonal Antibody","description":"\u003cp\u003eAkt, protein kinase B (PKB), is a serine\/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity of Akt\/PKB is to mediate cell survival. Akt\/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt\/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1\/alpha, 2\/beta and 3\/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,","offer_id":44092289581280,"sku":"BS65910","price":448.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/bioWORLD-Logo-New_1617713956_cdf46133-6aa5-43c6-b682-ec27c31ead02.png?v=1689722733","url":"https:\/\/rndmate.com\/products\/new-product-407177","provider":"알앤디메이트","version":"1.0","type":"link"}