{"product_id":"new-product-413042","title":"anti- Caspase 3 antibody","description":"\u003cp data-mce-fragment=\"1\"\u003eOur Anti-Caspase 3 Antibody (100µg) is a fundamental tool for researchers exploring apoptosis, a critical process in cellular biology. Caspase 3, also known as CPP32, is a central player in the execution phase of apoptosis. This antibody is meticulously designed to target Caspase 3, ensuring precise and reliable results in your experiments.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eWith 100µg of this antibody per vial, you'll have a substantial supply for multiple experiments, reducing the need for frequent restocking. Whether you're conducting Western blots, immunohistochemistry, or flow cytometry, this antibody consistently delivers high-quality performance.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eOur antibody is produced using advanced techniques and high-quality materials, guaranteeing specificity and sensitivity. Researchers can trust the accuracy of their data when using our Anti-Caspase 3 Antibody. Its reliability makes it indispensable for projects aimed at unraveling the intricate mechanisms of apoptosis and cell death.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eBy utilizing our Anti-Caspase 3 Antibody, you contribute to advancing the understanding of crucial cellular processes and their implications in health and disease. Empower your apoptosis research with confidence.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCaspase 3 antibody\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSize\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100µg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eliquid\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e≥95% as determined by SDS-PAGE\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRabbit\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003epolyclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIgG\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBACKGROUND\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCaspase 3, also named as CPP32, SCA-1 and Apopain, belongs to the peptidase C14A family. Caspase 3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase(PARP) at a '216-Asp-|-Gly-217' bond. Caspase 3 cleaves and activates sterol regulatory element binding proteins(SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6,-7 and-9. Caspase 3 is involved in the cleavage of huntingtin. The antibody can recognize p17 and p32 of Caspase 3.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMMUNOGEN INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ecaspase 3, apoptosis-related cysteine peptidase\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eApopain, CASP 3, CASP3, Caspase 3, Caspase 3\/p17, Caspase3, CPP 32, CPP32, CPP32B, Cysteine protease CPP32, Protein Yama, SCA 1, SREBP cleavage activity 1\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e32-35 kDa, 17 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAPPLICATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTested Application\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eELISA, WB, IHC, IF\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dilution\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:50-1:200\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUNIPROT INFORMATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt ID\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/www.uniprot.org\/uniprot\/P42574\"\u003eP42574\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMAGES\u003cbr\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab10013.jpg\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image1\/FNab10013.jpg\"\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eImmunohistochemistry of paraffin-embedded mouse heart tissue slide using FNab10013(CASP3 Antibody) at dilution of 1:100\u003cbr\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image2\/FNab10013.jpg\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image2\/FNab10013.jpg\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eImmunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using FNab10013 (caspase 3 antibody) at dilution of 1:50 and FITC-Conjugated Goat Anti-rabbit IgG(H+L)\u003cbr\u003e\u003cimg src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab10013.jpg\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/www.fn-test.com\/content\/uploads\/product\/images\/antibody\/image4\/FNab10013.jpg\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eJurkat cells were subjected to SDS PAGE followed by western blot with FNab10013(CASP3 antibody) at dilution of 1:1000\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"FineTest","offers":[{"title":"100µg \/ Rabbit \/ polyclonal","offer_id":44100101964000,"sku":"FNab10013","price":260.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/fine_test_logo_ec91faae-d9a8-40db-9a73-c94b7300f1f2.jpg?v=1690173946","url":"https:\/\/rndmate.com\/products\/new-product-413042","provider":"알앤디메이트","version":"1.0","type":"link"}