{"product_id":"new-product-815347","title":"GCH1 Rabbit pAb","description":"\u003cp\u003eThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":46092403409120,"sku":"A10616","price":298.0,"currency_code":"KRW","in_stock":true}],"url":"https:\/\/rndmate.com\/products\/new-product-815347","provider":"알앤디메이트","version":"1.0","type":"link"}