{"product_id":"new-product-815376","title":"COL4A1 Rabbit pAb","description":"\u003cp\u003eThis gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"Abclonal","offers":[{"title":"100ul","offer_id":46092408619232,"sku":"A10710","price":298.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/A10710_1.jpg?v=1721951611","url":"https:\/\/rndmate.com\/products\/new-product-815376","provider":"알앤디메이트","version":"1.0","type":"link"}