{"product_id":"nsj-f52112-0-4ml","title":"TSC2 Antibody, 0.4 ml","description":"\u003cp\u003eIn complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":48538123305184,"sku":"F52112-0.4ML","price":439.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_c8ffab02-80f6-4c51-8e75-c02ce6f8da39.jpg?v=1768358553","url":"https:\/\/rndmate.com\/products\/nsj-f52112-0-4ml","provider":"알앤디메이트","version":"1.0","type":"link"}