{"product_id":"nsj-f53216-0-4ml","title":"SMAD2 Antibody, 0.4 ml","description":"\u003cp\u003eSMAD2 is a receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2\/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml","offer_id":48538097254624,"sku":"F53216-0.4ML","price":439.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_fae9903a-cc33-4c49-a08e-767f171efb99.jpg?v=1768357904","url":"https:\/\/rndmate.com\/products\/nsj-f53216-0-4ml","provider":"알앤디메이트","version":"1.0","type":"link"}