{"product_id":"nsj-n1151-25ug","title":"S100A8 Antibody, 25 ug","description":"\u003cp\u003eThe S100 family of proteins are found in vertebrates and are characterized by two calcium-binding sites that have a helix-loop-helix conformation. The family of 24 is divided into three subgroups based on function: those with intracellular, intracellular plus extracellular, and extracellular regulatory effects. The calcium-binding protein S100A8, also called MRP8 or Myeloid-related protein 8, and Calgranulin A, forms a heterodimer with S100A9, called Calprotectin. The heterodimer is expressed by granulocytes, monocytes, and early differentiation states of macrophages, and is known to be an important pro-inflammatory mediator in acute and chronic inflammation. S100A8 and 9 are DAMPs, or Damage-associated molecular pattern molecules, and are able to activate receptors of the innate immune system, one being TLR4.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"25 ug","offer_id":48536648614112,"sku":"N1151-25UG","price":225.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_99fe2877-4d70-477c-8083-1b767e2568d4.jpg?v=1768313947","url":"https:\/\/rndmate.com\/products\/nsj-n1151-25ug","provider":"알앤디메이트","version":"1.0","type":"link"}