{"product_id":"nsj-r30728-100ug","title":"5-Lipoxygenase Antibody, 100 ug","description":"\u003cp\u003e5-Lipoxygenase is an enzyme that in humans is encoded by the ALOX5 gene. It is a member of the lipoxygenase family of enzymes which also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. The enzyme 5-lipoxygenase catalyzes 2 reactions in the formation of leukotrienes. Human ALOX5 contains three nuclear localization sequences (NLSs) and a phosphorylation site involved in nuclear localization. Compared with age-matched competent mice, the knockout mice developed less right heart hypertrophy. Pharmacologic inhibition or gene disruption resulted in a significant decrease of beta-amyloid production and gamma-secretase levels. ALOX5 activity is short-lived, apparently in part because of an intrinsic instability of the enzyme.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48536611848416,"sku":"R30728","price":449.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_641f90df-64cc-4460-80e2-de055421f86c.jpg?v=1768312732","url":"https:\/\/rndmate.com\/products\/nsj-r30728-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}