{"product_id":"nsj-r30967-100ug","title":"ABCG1 Antibody, 100 ug","description":"\u003cp\u003eABCG1 (ATP-binding cassette, subfamily G, member 1) also known as ABC8, is a protein that in humans is encoded by the ABCG1 gene. ABCG1 is a regulator of macrophage cholesterol and phospholipid transport. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The gene is mapped on 21q22.3. This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. ABCG1 is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. Inhibition of ABCG1 protein expression using an antisense strategy resulted in reduced HDL3-dependent efflux of cholesterol and choline-phospholipids. In macrophages, silencing of GPS2 by RNA interference reducedABCG1expression and diminished ABCG1-mediated cholesterol efflux.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48536605130976,"sku":"R30967","price":449.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_419e3d23-fef6-4be0-ae0f-994806db76c7.jpg?v=1768312507","url":"https:\/\/rndmate.com\/products\/nsj-r30967-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}