{"product_id":"nsj-r32307-100ug","title":"ITCH Antibody \/ AIF4, 100 ug","description":"\u003cp\u003eITCH is an ubiquitin-conjugating enzyme. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48536548180192,"sku":"R32307","price":449.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_2e7f85ca-e987-4484-8682-cfeedaa5f5d7.jpg?v=1768311078","url":"https:\/\/rndmate.com\/products\/nsj-r32307-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}