{"product_id":"nsj-rq6569-100ug","title":"FAM129B Antibody \/ MINERVA \/ NIBAN2, 100 ug","description":"\u003cp\u003eFAM129B\/Niban-like protein 1 (family with sequence similarity 129, member B) belongs to a poorly characterized family of Niban proteins that also includes FAM129A\/Niban and FAM129C\/Niban-like protein 2. FAM129A\/Niban is implicated in the ER stress response and is upregulated at the protein level in thyroid carcinoma. FAM129C\/Niban-like protein 2 is preferentially expressed in B-cells and is one of five biomarkers upregulated in whole blood from patients with colorectal carcinoma. FAM129B is broadly expressed and has been shown to be a downstream target of B-Raf in melanoma cells. Though FAM129B does not appear to regulate cell growth and division, phosphorylation of FAM129B by B-Raf is essential for the invasive potential of melanoma and non-melanoma cell lines. Deletion of FAM129B in melanoma cells significantly impairs B-Raf\/MEK\/Erk-dependent invasion into the extracellular matrix.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48536214208736,"sku":"RQ6569","price":449.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_e14836b6-d88b-4589-ae1f-5f6037ecdced.jpg?v=1768303753","url":"https:\/\/rndmate.com\/products\/nsj-rq6569-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}