{"product_id":"nsj-rq7105-100ug","title":"TCF4 Antibody \/ Transcription factor 4, 100 ug","description":"\u003cp\u003eTranscription factor 4 (TCF-4) also known as immunoglobulin transcription factor 2 (ITF-2) is a protein that in humans is encoded by the TCF4 gene located on chromosome 18q21.2. This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to \u0026gt;50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48536182194400,"sku":"RQ7105","price":449.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_4a977e45-e0af-4d4e-8df1-f6abf1f55784.jpg?v=1768303112","url":"https:\/\/rndmate.com\/products\/nsj-rq7105-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}