{"product_id":"nsj-rq7208-100ug","title":"Toll-like receptor 4 Antibody \/ TLR4, 100 ug","description":"\u003cp\u003eTLR4, the human homolog of Drosophila Toll, is a type I transmembrane protein with an extracellular domain consisting of a leucine-rich repeat region and an intracellular domain homologous to that of human interleukin-1 receptor. The TLR4 gene is mapped to chromosome 9q32-q33 by fluorescence in situ hybridization. It detects lipopolysaccharide from Gram-negative bacteria and is thus important in the activation of the innate immune system. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48536176263392,"sku":"RQ7208","price":449.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_5c6b98d1-ff3f-4b64-8718-7bdbca651e5d.jpg?v=1768302989","url":"https:\/\/rndmate.com\/products\/nsj-rq7208-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}